The Study Monitoring Committee (SMC) functions as an arm of the MTN Steering Committee to provide peer review of the conduct of MTN studies, with an emphasis on key performance indicators, such as participant accrual and retention, adherence to the protocol and the intervention, and data quality and laboratory quality. Requirements for the SMC review are contained within each study protocol.
For more information on the study review process, please see MTN's Manual of Operational Procedures, Section 16, Study Oversight.