MTN is excited to share the news that the Lima, Peru and Blantyre, Malawi sites for MTN-035, fondly called the DESIRE study, have activated and are beginning to enroll study participants. DESIRE is exploring three placebo methods for the delivery of a rectal microbicide – a douche, suppository and fast-dissolving rectal insert – in 210 transgender men and women and cisgender men who have sex with men.