MTN-028 is a Phase I study that seeks to evaluate the safety and systemic and local pharmacokinetics (PK) of vaginal rings (VRs) containing varying dose strengths of the antiretroviral (ARV) drugs Vicriviroc (MK-4176) and MK-2048. The study will enroll approximately 18 women at one U.S. site beginning in mid to late 2015 and will take approximately 6-9 months to conduct.
MTN-027 is a Phase I study that seeks to evaluate the safety and systemic and local pharmacokinetics (PK) of vaginal rings (VRs) containing (1) the antiretroviral (ARV) drug Vicriviroc (MK-4176); (2) the ARV drug MK-2048; or (3) the two ARV drugs in combination. The study will enroll pproximately 48 women at two U.S. sites in mid to late 2015 and will take approximately 6-9 months to conduct.